By CAPosts 29 June, 2020 - 05:41pm 18 views
© Provided by Oxford University Researchers Day found that the treatment used against HIV has no beneficial effect on Covid patients. Photo Marco Peláez / Archive
Londres, A combination of antiviral drugs used to treat HIV had no beneficial effect on patients hospitalized with Covid-19 in a large-scale randomized trial, British scientists said Monday.
Scientists in charge of the "RECOVERY" trial at the University of Oxford argued that the results "convincingly rule out any significant mortality benefits of lopinavir-ritonavir in the patients hospitalized with Covid-19 we studied."
Scientists found no difference in mortality, length of hospitalization or risk of being connected to a respirator, when they compared 596 patients receiving lopinavir-ritonavir versus 3,376 patients in a control group.
Kaletra from AbbVie Inc is a combination of the drugs lopinavir and ritonavir, which are used to fight HIV. The company had increased its supplies while determining whether it could be used to treat the Covid-19.
"These preliminary results show that for patients hospitalized with Covid-19 and not connected to a fan, lopinavir-ritonavir is not an effective treatment," said Peter Horby, lead researcher at the trial.
Scientists were unable to draw conclusions about the effectiveness of drug mixing in respirator patients due to difficulty administering them.
The combination of lopinavir-ritonavir is also being studied in a World Health Organization trial.