Alzheimer’s disease is a public health crisis that is expanding, yet a significant percentage of dementia could be delayed – and in some cases prevented – by early intervention.
Nine of my bills have been signed into law. This year, legislation I authored focused on protecting the environment, increasing consumer protections, expanding healthcare, Alzheimer’s disease detection, education, and more. #SD19 sd19.senate.ca.gov/2021-2022-legislation pic.twitter.com/NQBykS23j9
#NEW: Mass' largest health insurer, @BCBSMA, announces it will not cover new Alzheimer's drug Aduhelm. “The clinical evidence for Aduhelm, though promising, does not clearly demonstrate that the potential benefits of the drug outweigh the known risks." www.wpri.com/target-12/massachusetts-largest-health-insurer-wont-cover-new-alzheimers-drug-aduhelm/
13 October, 2021 - 04:15am
"The social and economic benefits of accelerating clean energy transitions are huge, and the costs of inaction are immense."
The World Energy Outlook makes use of a scenario approach to examine future energy trends relying on the WEM. For the World Energy Outlook 2021 (WEO-2021), four scenarios were modelled: the Net Zero Emissions by 2050 Scenario (NZE), the Announced Pledges Scenario (APS), the Stated Policies Scenario (STEPS), and the Sustainable Development Scenario (SDS).
This year, the full World Energy Outlook report (PDF) is provided free of charge. In addition, we are also providing a WEO-2021 Free Dataset that includes global data for all scenarios (SDS, APS, STEPS, NZE) and selected data for key regions and countries for 2030 and 2050, as well as historical data for 2010, 2019 and 2020. Access to this dataset will be free of charge for non-commercial usage. An Extended Dataset with more detailed data at global and regional or country level, as well as all chapter figures, is available for purchase.
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12 October, 2021 - 03:41pm
On Monday, researchers showed that the drug bumetanide, normally used to manage fluid retention for conditions like hypertension, led to a reversal of Alzheimer’s symptoms in laboratory mice as well as human brain cells. And through a study of the health records of millions of patients, those same researchers found that people over 65 who took bumetanide regularly were 35–75 percent less likely to get diagnosed with Alzheimer’s.
The findings, published in Nature Aging, hinges around the gene APOE, which mediates fat metabolism in mammals but is also known to be a major risk factor for Alzheimer’s. Through an analysis of APOE gene records in Alzheimer’s patients, along with the data of 1,300 existing drugs, the researchers found that bumetanide might be associated with reversing the effects of altered APOE genes. The drug’s mechanisms for changing fluid retention in cells also plays a role in how neurons in the brain trigger electrical signaling, so it seems worth exploring.
It seems the researchers’ intuition about the drug was right. And Bumetanide’s potential to treat Alzheimer’s is bolstered by the fact that it is already FDA-approved, and has a safety record that stretches back for decades. “This is a drug with a well-established safety record, so it could reach patients much faster than typical drug development takes,” Gladstone Institute researcher and study coauthor Yadong Huang said in a statement.
That’s great news for getting a clinical trial started to truly test whether bumetanide can help combat Alzheimer’s. Huang and his team are already in advanced talks with other medical centers to get one started.
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Marist High School said an investigation found that kneeling was not isolated to one song, but it acknowledged students "were hurt by these actions."
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A replica of a mysterious pre-Hispanic sculpture of an Indigenous woman was chosen Tuesday to replace a statue of Christopher Columbus on Mexico City’s most prominent boulevard. The statue was unearthed in January in the Huasteca region, near Mexico’s Gulf coast. The National Institute of Anthropology and History said at the time the statue was similar to depictions of a fertility goddess of the Huastec culture.
Clean energy advocate Vote Solar has issued a new report as the S.C. Public Service Commission prepares to take comments later this month on Duke Energy's revised Integrated Resource Plan proposal.
I was 16 years old the day I found out I was pregnant, peeing on a stick in my best friend's bathroom while she and her older sister waited anxiously outside the door. We huddled together, staring at the positive pregnancy test for what seemed like ages.