Blink-182’s Mark Hoppus says he has stage 4 diffuse large B-cell lymphoma

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Fox News 17 July, 2021 - 03:55pm 29 views

What kind of cancer does mark from Blink 182 have?

Blink-182's Mark Hoppus has revealed new details about his cancer diagnosis. The 49-year-old rocker shared that he has “diffuse large B-cell lymphoma Stage 4-A” during a Twitch live stream with fans, which was captured and reuploaded by a Blink 182 fan account on YouTube. Page SixBlink-182's Mark Hoppus reveals Stage 4 lymphoma diagnosis

Mark Hoppus Revealed More Details About His Stage IV Cancer Diagnosis

msnNOW 17 July, 2021 - 07:01pm

Mark Hoppus, frontman and bassist for the band Blink-182, revealed last month that he had been undergoing chemotherapy for three months. And in a live video this week, Hoppus, 49, shared more details about his diagnosis, the type of cancer he's dealing with, and how chemotherapy has been going.

In a live Q&A with fans in Chile, Hoppus shared that his cancer is “not bone-related, it's blood-related. My blood's trying to kill me.” Specifically, he's been diagnosed with diffuse large B-cell lymphoma stage 4-A. “It's entered enough parts of my body that I'm stage IV, which I think is the highest that it goes,” he said.

Hoppus also gave an update on how his chemotherapy has been going. “Let me tell you something that is real and it absolutely sucks: A side effect of the chemotherapy is you get something called ‘chemo brain,’” he explained. “And for me, I forget things that I should have on-call, like names, song titles, anything. People will be talking to me and five minutes later I'll ask them a question, and they'll be like, ‘I just told you that five minutes ago.’”

At the time of the recording, Hoppus said he was preparing to go in for a PET scan, which would determine how well the chemotherapy was working. If it doesn't seem to be helping, a bone marrow transplant may be necessary. But regardless of the results, he will likely need another three rounds of chemo, he said. 

Diffuse large B-cell lymphoma is the most common form of non-Hodgkin lymphoma in the U.S., the American Cancer Society (ACS) explains. This type of cancer affects the body's lymph system, including the white blood cells. It typically grows quickly and progresses aggressively, but does tend to respond well to treatment, the ACS says. There are several treatment options for non-Hodgkin lymphoma, such as chemotherapy, radiation, immunotherapy, the Mayo Clinic says.

In most cases, doctors don't know what caused someone's non-Hodgkin lymphoma and many people who develop this type of cancer don't have any obvious risk factors, the Mayo Clinic explains. But there are some factors, such as taking immune-suppressing drugs or having certain viral infections (like HIV or Epstein-Barr), that can make this cancer more likely. Interestingly, Hoppus shared that his mom had the exact same type of cancer previously and was able to treat it effectively.

Hoppus first spoke publicly about his situation in late June and continues to keep a positive attitude about what the future may hold. “Oh, we're beating this cancer," he said in the video this week. "It's just a matter of time."

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Blink-182's Mark Hoppus revealed he has with Stage 4 'blood-related' cancer

Insider 17 July, 2021 - 12:00am

During a recent Twitch Q&A with fans, the "Blink-182" singer revealed that his cancer is "blood-related" instead of "bone-related." 

"My cancer's not bone-related, it's blood-related. My blood's trying to kill me," Hoppus said, according to a video of the livestream shared online. 

Hoppus said he was diagnosed with diffuse large B-cell lymphoma stage 4-A.

According to the Lymphoma Research Foundation, diffuse large B-cell lymphoma is an "aggressive" non-Hodgkin lymphoma that affects the white blood cells.

"My classification is diffuse large B-cell lymphoma stage IV-A, which means, as I understand it, it's entered four parts of my body," Hoppus said. "I don't know how exactly they determine the four-part of it, but it's entered enough parts of my body that I'm stage IV, which I think is the highest that it goes. So, I'm stage IV-A." 

He first spoke about his cancer diagnosis in June, saying that "it sucks and I'm scared."

Hoppus one week later opened up about undergoing chemotherapy and the difficulties he experienced from the treatment. He previously said some rounds of chemotherapy made him feel like "a poisoned electrified zombie."

During the Q&A, Hoppus said the diagnosis brought him and his mother closer. 

"Oddly enough, we have the exact form of cancer," Hoppus said. "And she beat it, so I've been able to talk to her and bond with her quite a bit." 

The musician said his mother has "beaten cancer three times," including two cases of breast canser. 

Hoppus said he was scheduled to attend a medical appointment to determine if chemotherapy worked. 

"Ideally, I go in tomorrow and they say, 'Congratulations, your chemotherapy has worked and you're all done and you'll never have to think about this cancer again for the rest of your life," Hoppus said. 

If not, Hoppus said he'll need to pursue alternatives like a bone marrow transplant. 

Following Hoppus' initial announcement of his diagnosis, his former bandmates Travis Barker and Tom DeLonge offered their support. 

"Mark is my brother and I love and support him," Barker said in a statement to E! News. "I will be with him every step of the way on stage and off and can't wait for us to play together again soon." 

Blink-182's Mark Hoppus Opens Up About His Cancer Diagnosis: "My Blood's Trying to Kill Me"

Health.com 16 July, 2021 - 04:32pm

"My cancer is not bone-related; it's blood-related. My blood's trying to kill me," Hoppus said in a recent video Q&A uploaded to YouTube.

The musician was diagnosed with the cancer in late April. He made the news public through a tweet back in June.

Since his announcement, Hoppus has been candid about his chemotherapy experience. "Everything about chemo sucks except the part where it hopefully saves my life," he tweeted on July 2.

The first round of chemo made him feel as though he "was a zombie that fell onto an electric fence and was just being shocked," Hoppus said in the Q&A. Each round of chemo after has had different effects, with the second making him feel "weak, tired," and as though he had the "worst flu ever." The third round made him nauseas. He's also says he has "chemo brain": "I forget things that I should just have on call, like people's names, song titles—anything. I just forget stuff."

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While he's been candid about his treatment, this is the first time he's said what type of cancer he was diagnosed with—also revealing in the Q&A that his DLBCL is stage IV-A. "I don't know exactly how they determine the 'IV' part of it, but it's entered enough parts of my body that I'm stage IV which is, I think, the highest it goes."

As it turns out, Hoppus' mom also had (and survived) DLBCL. "I've been able to talk with her and bond with her quite a bit," he said.

As Hoppus continues his own fight with the disease—"We're beating this cancer. It's just a matter of time," he says—here's what you should know about DLBCL.

DLBCL is the most common type of non-Hodgkin lymphoma, a cancer that starts in white blood cells called lymphocytes. Specifically, DLBCL affects the body's B-lymphocytes, which make antibodies to fight infections, according to the Lymphoma Research Foundation.

DLBCL can develop in the lymph nodes or in areas outside the lymph nodes, such as the gastrointestinal tract, testes, thyroid, skin, breast, bone, brain, or virtually any organ of the body. It may affect just one part of the body or spread throughout.

Every year, more than 18,000 people are diagnosed with DLBCL, according to the Lymphoma Research Foundation.

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"[DLBCL] usually starts as a quickly growing mass in a lymph node deep inside the body, such as in the chest or abdomen, or in a lymph node you can feel, such as in the neck or armpit," according to the American Cancer Society (ACS). "It can also start in other areas such as the intestines, bones, or even the brain or spinal cord."

Oftentimes, "the first sign of DLBCL is a painless, rapid swelling in the neck, underarms, or groin that is caused by enlarged lymph nodes," the Lymphoma Research Foundation reports. The swelling may be painful for some people.

Besides the tumors themselves, other symptoms of DLBCL include fever, night sweats, and weight loss, per the National Cancer Institute. Other symptoms may be fatigue, loss of appetite, and shortness of breath.

While DLBCL can develop in someone of any age, even a child, "the occurrence of DLBCL generally increases with age, and most patients are over the age of 60 at diagnosis," according to the Lymphoma Research Foundation.

Besides being older, other risk factors for developing a non-Hodgkin lymphoma like DLBCL include:

Again, DLBCL is aggressive, meaning it tends to grow quickly. Still, the Lymphoma Research Foundation considers the disease "potentially curable." In fact, the ACS reports that about 75% of people will have no signs of DLBCL after the initial treatment, and about half are cured. Important to note, the prognosis is typically more favorable for those who have a lower stage of the disease.

"Limited-stage disease (stages I and II) represents lymphoma affecting only one area of the body, while advanced-stage disease (stages III and IV) indicates that lymphoma has spread to several organs," according to the Lymphoma Research Foundation. Patients with DLBCL actually often have advanced-stage disease, but treatment can still be very effective.

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The type of treatment someone will undergo depends on a number of factors, most notably the type of lymphoma and the extent (aka the stage) of the disease, per the ACS. But most often, the treatment is a combination of chemo and the monoclonal antibody rituximab. Referred to as R-CHOP, the treatment is most often given in cycles three weeks apart.

For someone with stage IV DLBCL, like Hoppus, most doctors will give 6 cycles of R-CHOP as first-line treatment. After several cycles, doctors may order imaging tests, such as a PET/CT scan, to see how well treatment is working.

Hoppus was scheduled to have a PET scan this week to see if his first three rounds of chemo treatment are working. Although he hasn't posted about the results of that scan yet, he can likely expect more rounds of chemo. As he explained in his Q&A video, even if the chemo has already worked completely, his doctors will still want him to undergo three more rounds of chemo "just to make sure." He'll also undergo more rounds if the chemo has been making some progress. If they find that the chemo has not worked as they had hoped, they will have to discuss other treatment options, which Hoppus said might include a bone marrow transplant.

"I'm going to beat this through chemotherapy or through bone marrow transplants, but either way I'm determined to kick cancer's ass directly in the nuts," he tweeted on July 10. "Love to you all. Let's. Heckin. Go."

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